Bet v 1 homologues in strawberry identified as IgE-binding proteins and presumptive allergens
نویسندگان
چکیده
منابع مشابه
Detection of specific IgE antibodies in sera of Japanese birch-allergic patients using recombinant allergens Bet v 1, Bet v 2 and Bet v 4.
BACKGROUND Birch pollen is the major allergen in pollinosis in northern Japan. IgE reactivity to individual birch pollen allergens has been shown to differ between populations of birch pollen-allergic patients living in different countries. In this study, we examined the IgE profiles to recombinant birch pollen allergens in birch-sensitive patients living in Sapporo. METHODS This study used t...
متن کاملPathogenesis-related (PR)-proteins identified as allergens.
Type 1 allergies are recognized as an important disease affecting around 25% of the population of industrialized countries of the Northern hemisphere. Allergic patients produce specific IgE antibodies after frequent exposure to either inhaled or nutritive allergens. Of the plant allergens listed in the Official Allergen Database of the International Union of Immunological Societies, approx. 25%...
متن کاملIgE, IgG4 and IgA specific to Bet v 1-related food allergens do not predict oral allergy syndrome
BACKGROUND Birch pollen-associated plant food allergy is caused by Bet v 1-specific IgE, but presence of cross-reactive IgE to related allergens does not predict food allergy. The role of other immunoglobulin isotypes in the birch pollen-plant food syndrome has not been investigated in detail. METHODS Bet v 1-sensitized birch pollen-allergic patients (n = 35) were diagnosed for food allergy b...
متن کاملCrystallographically Mapped Ligand Binding Differs in High and Low IgE Binding Isoforms of Birch Pollen Allergen Bet v 1
The ability of pathogenesis-related proteins of family 10 to bind a broad spectrum of ligands is considered to play a key role for their physiological and pathological functions. In particular, Bet v 1, an archetypical allergen from birch pollen, is described as a highly promiscuous ligand acceptor. However, the detailed recognition mechanisms, including specificity factors discriminating bindi...
متن کاملIgE-Binding Properties of Recombinant Food Allergens
Recombinant DNA technology is a common procedure to produce allergenic proteins in vitro. To date, more than 40 food allergens from fruits, vegetables, nuts, milk and seafood have been expressed as recombinant proteins. Since recombinant proteins can be produced in large quantities and in controlled quality, they promise to be suitable tools for precise diagnostics and research applications. "H...
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ژورنال
عنوان ژورنال: Allergy
سال: 2004
ISSN: 0105-4538,1398-9995
DOI: 10.1111/j.1398-9995.2004.00585.x